Click here for directions. Nestled in the southern heart of Mendoza Province along the scenic Argentine Wine Route is the city of San Rafael, which boasts the most breathtaking views in the region. Often described as a place that suits all needs, San Rafael is a center of distinction offering sidewalk cafés, tree-lined boulevards, green spaces, vineyards and wineries, museums, and a number of resorts and lodges. It is a safe city with little to no crime, and as the province's second largest city, it enjoys over 330 days of annual sunshine. With the Sierra Pintada and Andes Mountains as its backdrop, it lies in close proximity to some of Argentina’s most exciting tourist attractions including the Rio Atuel, the Rio Diamante, Valle Grande, and one of South America's greatest ski resorts, Las Leñas.